Description: Systems Chemical Biology : Methods and Protocols, Hardcover by Ziegler, Slava (EDT); Waldmann, Herbert (EDT), ISBN 1493988905, ISBN-13 9781493988907, Like New Used, Free P&P in the UK
This volume explores the latest available wet-lab techniques and computational methods to study in-cell small-molecule behavior and interactions with their targets. The chapters in this book discuss topics such as disease-relevant models for chemical biology studies, target engagement using cellular thermal shift assay or bioluminescence resonance energy transfer; visualization of bio-active small molecules Raman microscopy; (phospho-)proteomics and transcriptomics for mode-of-action studies, CRISPR/Cas9-based chemogenomic profiling in mammalian cells; predicting drug interactions using computational approaches; comparison of compound-induced profiles using high-content imaging or cancer cell line panels and web-based tools for polypharmacology prediction. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Cutting-edge and thorough, Systems Chemical Biology: Methods and Protocols is a valuable resource for novice or expert scientists and researchers trying to initiate or continue their chemical biology studies at a systems level.
Price: 129.97 GBP
Location: Castle Donington
End Time: 2024-12-04T04:08:19.000Z
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Book Title: Systems Chemical Biology : Methods and Protocols
Item Height: 254 mm
Item Width: 178 mm
Series: Methods in Molecular Biology
Author: Slava Ziegler, Herbert Waldmann
Publication Name: Systems Chemical Biology: Methods and Protocols
Format: Hardcover
Language: English
Publisher: Humana Press Inc.
Subject: Engineering & Technology, Biology
Publication Year: 2018
Type: Textbook
Item Weight: 843 g
Number of Pages: 315 Pages
