Description: We're starting up international shipments to most countries again in a trial run. As long as the packages arrive in a reasonable time frame, we'll keep shipping to those countries. The majority of countries we're not shipping to right now are because the United States Postal Service has suspended has service there right now. We have excluded most of those countries. In addition to those, we also cannot ship to the following countries at this time: Cuba, Mayonette, South Sudan, Syria, and Timor-Leste. If any orders comes through for the excluded countries or any of the additional countries, we will cancel them immediately and refund your money. We'll continue to check back on those countries to see if those suspension have been lifted. However, if you live in one of those countries and believe it's lifted now, let us know and we'll check on it. Shipping rates have risen significantly since we suspended international shipping and it's now $19.95 U.S. dollars for the first order in the shipment in international orders. For each additional order in the same shipment, it's $1.00 U.S. dollar more, so ordering a higher quantity of the item will save you on shipping per item. As long as the packets are dry and unmixed, they will keep for at least a year. Please Note: Import duties, taxes, and charges are not included in the item price or shipping cost. These charges are the buyer's responsibility. Please check with your country's customs office to determine what these additional costs will be prior to buying. Brought to you by a previous top seller of pseudocatalase on eBay..... Here are some quotes from studies using pseudocatalase on vitilgo and for gray hair: "...pseudocatalase treatment stopped the progression of active vitiligo in 95% of cases;(ii) the repigmentation process was independent of disease duration,and even patients with long lasting disease presented excellent recovery." Schallreuter,K. U., Moore, J., Wood, J. M., Beazley, W. D., Gaze, D. C., Tobin, D.J., . . . Hibberts, N. A. (1999). In Vivo and In Vitro Evidence for Hydrogen Peroxide (H2O2) Accumulation in the Epidermis of Patientswith Vitiligo and its Successful Removal by a UVB-ActivatedPseudocatalase. Journal of Investigative Dermatology Symposium Proceedings, 4(1),91-96. doi:10.1038/sj.jidsp.5640189 "Topical pseudocatalase, used in combination with UVB and a topical calcium preparation, has been reported in an open study to lead to complete repigmentation in 90% of treated patients." Kostovic,K., Nola, I., Bucan, Z., & Situm, M. (2003). Treatment ofVitilgo: Current Methods and New Approaches. ActaDermatovenerol Croat, 11(3),163-170. "The topically applied pseudocatalase can arrest (stop) the progression of the disease in 95% of adult patients and initiate repigmentation in 60% of the same patient group." Schallreuter,K. U., Krüger, C., Würfel, B. A., Panske, A., & Wood, J. M.(2008). From basic research to the bedside: Efficacy of topicaltreatment with pseudocatalase PC-KUS in 71 children withvitiligo. International Journalof Dermatology, 47(7),743-753. doi:10.1111/j.1365-4632.2008.03660.x "Results: One hundred per cent cessation (of the progression of pseudocatalase) was observed in 70 of the 71 children. More than 75% repigmentation was achieved in 66 of 71 patients on the face/neck, 48 out of 61 on the trunk, and 40 out of 55 on the extremities…" Schallreuter,K. U., Krüger, C., Würfel, B. A., Panske, A., & Wood, J. M.(2008). From basic research to the bedside: Efficacy of topical treatment with pseudocatalase PC-KUS in 71 children withvitiligo. International Journalof Dermatology, 47(7),743-753. doi:10.1111/j.1365-4632.2008.03660.x “The removal of H2O2 from the epidermis of these patients with a topical supplementation of a NB-UVB311nm activated pro-pseudocatalase PC-KUS results in correction of the redox balance in the skin of these patients, followed by repigmentation of the lost skin and hair colour.” Salem,M. E. (2017). Effect of Hydrogen Perioxide on Dicarbonyl - XyluloseReductase in Human Vitiligo Cells. Journalof Adanced Trends in Basic and Applied Science, 1(2),208-211. “...studies have indicated that another enzyme, called pseudocatalase, may prevent generation of gray hair.” Cwynar,A., Olszewska-Slonina, D., & Pukownik, E. (2015). The Effect ofOxidative Modifications of Amino Acid Residues in the Active Centerof Tyrosinase on the Process of Graying. Journalof Education, Health, and Sport, 5(9),102-108. “The repigmenting potential of grey hairs, combined with vitiligo - pseudocatalase experience of repigmenting eyelashes and the new findings of catalase depletion in grey hair follicles, led to the development of numerous ‘anti-greying’ strategies and products.” Seiberg,M. (2013). Age-induced hair greying - the multiple effects of oxidative stress. International Journal of Cosmetic Science, 35(6),532-538. doi:10.1111/ics.12090 “In vitiligo, return of functioning melanocytes and repigmentation of the lost skin color has been proven through intervention with an active pseudocatalase PC-KUS complex (Schallreuter et al. 2008B; Wood et al., 2009) Based on those results, it is tempting to propose that redox correction could prevent hair graying and/or reverse gray hair to the original color. In the light of the earlier data, this seems a promising strategy.” Schallreuter,K. U., Mohamed M. A. E. L. Salem, Hasse, S., & Rokos, H. (2010).The redox - biochemistry of human hair pigmentation. PigmentCell & Melanoma Research, 24(1),51-62. doi:10.1111/j.1755-148x.2010.00794.x "None of the patients experienced any serious complications. Some of the patients experienced increased sweating after application of the cream, which subsided without any intervention." Schallreuter,K. U., Krüger, C., Würfel, B. A., Panske, A., & Wood, J. M.(2008). From basic research to the bedside: Efficacy of topical treatment with pseudocatalase PC-KUS in 71 children with vitiligo. International Journal of Dermatology, 47(7),743-753. doi:10.1111/j.1365-4632.2008.03660.x "After complete repigmentation the treatment was stopped and there was no new onset of vitiligo observed. So far, these fully recovered patients have remained stable for up to 5 y. Conversely, if the treatment was terminated before complete repigmentation,there was a rebound phenomenon observed in all cases." Schallreuter,K. U., Moore, J., Wood, J. M., Beazley, W. D., Gaze, D. C., Tobin, D.J., . . . Hibberts, N. A. (1999). In Vivo and In Vitro Evidence forHydrogen Peroxide (H2O2) Accumulation in the Epidermis of Patients with Vitiligo and its Successful Removal by a UVB-Activated Pseudocatalase. Journal of Investigative Dermatology Symposium Proceedings, 4(1),91-96. doi:10.1038/sj.jidsp.5640189 "At present time, treatment is stopped when 100% repigmentation has been obtained. Otherwise, low dose maintenance therapy is continued." Schallreuter,K. U., Krüger, C., Würfel, B. A., Panske, A., & Wood, J. M.(2008). From basic research to the bedside: Efficacy of topical treatment with pseudocatalase PC-KUS in 71 children with vitiligo. International Journal of Dermatology, 47(7),743-753. doi:10.1111/j.1365-4632.2008.03660.x About Vitiligo: The most prominent symptom of vitiligo is white patches of skin. Those patches may spread around the body, but experts don't know how to determine if it will spread. Vitiligo mostly shows up in people underage 40, more in people aged 10 to 30 than others. Doctors can diagnosis it. The condition can cause complications including being more prone to sunburns in the white patches, inflammation of the iris part of the eye, and partial hearing loss. People with vitiligo that is particularly visible also have a tendency to struggle more with issues of self-esteem and confidence. Our Pseudocatalase Powder Mixture: This pseudocatalase is made with high quality ingredients, to the purest possible. It has no fillers or additives. The weight of the pseudocatalase has no bearing on the effectiveness. One order of pseudocatalase makes one order of it, which can last 3 to 6 months or more if properly cared for and the directions included are followed. This product is ran, packed, and sold by a partner of a former top seller of pseudocatalase on eBay. This is a high-quality formulation of pseudocatalase by a partner, who mixed, packed, and shipped thousands of orders. Ingredients: Sodium Bicarbonate, Manganese(II) Chloride Anhydrous, Tetrasodium EDTA. This item is NOT prescribed. No prescription is needed for this item and it is not a drug. For external use only! Do NOT eat, drink or otherwise ingest it. For direct application on skin or hair only, after following the directions to prepare it. Ships to anywhere in the United States for free with standard shipping. An extra fee is charged for faster shipping and international shipping. International Buyers – Please Note: Import duties, taxes, and charges are not included in the item price or shipping cost. These charges are the buyer's responsibility. Please check with your country's customs office to determine what these additional costs will be prior to bidding or buying. We're happy to answer any questions related to our pseudocatalase! Instructions for Preparing One Serving of Pseudocatalase from the Powders: 1.Keep the contents of Packets “A” and “B” completely separate until you’re ready to prepare the solution for use. It will be usable for about 3-6 months if kept in a clean plastic bottle and stored in the refrigerator.When it turn a dark brown color, it has gone bad and should be thrown out. 2.Studies recommend using pseudocatalase for about a year or two or until complete repigmentation. Studies considered it successful if the progression of depigmentation (vitiligo or gray hair) was stopped and/or if repigmentation was observed. 3.When you’re ready, mix the contents of Packets “A” and “B”with 400 mL of distilled, reverse osmosis,or demineralized water. Some measuring cups will have marks to measure milliliters. 4.The powders will produce a small reaction in the water but won’t fizz. This should take under 5 minutes. 5.After the reaction, you’re ready to put it into a bottle and refrigerate. 6.It’s not recommended to put the pseudocatalase into a skin cream,as it goes bad much faster that way, possibly in a matter of weeks instead of months. In addition, particles may settle at the bottom of the mixture when sitting in the refrigerator. 7.When taking it out of the fridge to use, shake it for 5 seconds or so if any of the mixture is on the bottom of the bottle. 8.Apply mixture to the skin or hair you’re treating twice a day,dampening the skin or hair. It’s not necessary for it to be dripping. You can lightly massage it into the skin or hair if you like. Put it on before you apply any hair gel, oil, or other hair products. Wait a few minutes for the pseudocatalase to absorb into your skin before applying hair products. 9.Ultraviolet (UV) light is necessary for the product to work properly.You’ll need to get 15-30 minutes of UV exposure at the skin or hair sites being treated at least two or three times a week. This can be achieved through the sun or a tanning bulb. You don’t need heavy UV light. A somewhat sunny day or a tanning bulb for a light tan is plenty. This helps stimulate your pigment cells (melanocytes). It can be done anytime and doesn’t need to match the time you apply the pseudocatalase. Don’t look directly at the UV light. It could hurt your eyes. Be sensible about the amount of time you spend in the sun or tanning. Excessive time in the sun or under a tanning bulb can cause skin damage and/or cancer. You are responsible for your own actions.
Price: 18.98 USD
Location: Tucson, Arizona
End Time: 2024-08-29T19:12:31.000Z
Shipping Cost: 0 USD
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Item Specifics
All returns accepted: ReturnsNotAccepted
Type: Skin Care
Volume: Mixes into 400 mL of liquid pseudocatalase
Brand: Unbranded