Description: Chromosomal Imbalance Theory of Cancer : The Autocatalyzed Progression of Aneuploidy is Carcinogenesis, Hardcover by Rasnick, David, ISBN 1578087376, ISBN-13 9781578087372, Like New Used, Free shipping in the US Rasnick, who worked in the pharmaceutical/biotech industry to develop protease inhibitors and founded three biotech companies, explains the chromosomal imbalance (aneuploidy) theory of cancer, as opposed to the gene mutation theory. He describes how gene mutations are not powerful enough to cause cancer; how cancer is initiated and why progression takes years or decades; and the global or macroscopic characteristics that identify cancer: anaplasia, autonomous growth, metastasis, abnormal cell morphology, DNA indices from to over 2, genetic instability, and the high level of membrane-bound and secreted proteins responsible for invasiveness and loss of contact inhibition. He explains the common failure of chemotherapy and why cancer cells often become drug resistant, measures for detecting cancer and monitoring its progression, and non-toxic strategies for therapy and prevention. Distributed by CRC Press. Annotation ©2012 Book News, Inc., Portland, OR ()
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Book Title: Chromosomal Imbalance Theory of Cancer : The Autocatalyzed Progre
Number of Pages: 360 Pages
Language: English
Publication Name: Chromosomal Imbalance Theory of Cancer : The Autocatalyzed Progression of Aneuploidy Is Carcinogenesis
Publisher: CRC Press LLC
Item Height: 0.9 in
Publication Year: 2011
Subject: Life Sciences / Cell Biology, Life Sciences / Genetics & Genomics, Endocrinology & Metabolism, Oncology
Item Weight: 22.4 Oz
Type: Textbook
Author: David Rasnick
Item Length: 9.3 in
Subject Area: Science, Medical
Item Width: 6.3 in
Format: Hardcover
